Hermano

Sonequa Martin-Green

Michael Burnham

Doug Jones

Saru

Mary Wiseman

Sylvia Tilly

Anthony Rapp

Paul Stamets

Wilson Cruz

Hugh Culber

Blu del Barrio

Adira Tal

David Ajala

Cleveland 'Book' Booker

Callum Keith Rennie

Rayner

James Frain

Sarek

Sean Connolly Affleck

Lt. Connolly

Arista Arhin

Young Michael Burnham

Mia Kirshner

Amanda Grayson

Tig Notaro

Jett Reno

Rachael Ancheril

Cmdr. Nhan

Hannah Cheesman

Lt. Cmdr. Airiam

Julianne Grossman

Discovery Computer (voice)

Ronnie Rowe

RA Bryce

Oyin Oladejo

Joann Owosekun

Patrick Kwok-Choon

Rhys

Emily Coutts

Keyla Detmer

Sara Mitich

Nilsson

Raven Dauda

Dr. Pollard

David Benjamin Tomlinson

Linus

Liam Hughes

Young Spock

Ethan Peck

Spock (voice)